Start by gathering all the necessary ingredients. Panettone requires all-purpose flour, active dry yeast, granulated sugar, salt, warm milk, eggs, egg yolks, softened butter, vanilla extract, and orange zest for the dough. For the filling, include raisins, candied orange peel, and candied lemon peel.
Optional rum for soaking the raisins adds a nice depth of flavor but can be replaced with warm water if preferred. Having a panettone paper mold or a deep round baking pan lined with parchment paper ensures the bread retains its signature tall shape.